纳布啡与舒芬太尼用于老年患者腹腔镜下胆囊切除术后镇痛的临床效果观察

Clinical Observation of Nalbuphine and Sufentanil for Analgesia after Laparoscopic Cholecystectomy in Elderly Patients

目的探讨纳布啡与舒芬太尼用于老年患者腹腔镜下胆囊切除术后镇痛的临床效果。方法将2017年5月至2018年5月我院收治的112例接受腹腔镜下胆囊切除术的老年患者分为两组:即对照组和试验组,每组各56例。对照组给予舒芬太尼术后镇痛,试验组给予盐酸纳布啡注射液术后镇痛,比较观察两组患者的VAS疼痛评分及镇静Ramsay评分,并评价两组患者术后恶心、呕吐及嗜睡临床并发症的发生率及住院时间。结果两组患者VAS镇痛及镇静Ramsay评分的比较,B组患VAS镇痛及镇静Ramsay评分均低于A组,比较差异有统计学意义(P<0.05);B组患者恶心、呕吐及嗜睡临床并发症的发生率明显低于A组,比较差异有统计学意义(P<0.05);B组患者的住院时间明显短于A组,比较差异有统计学意义(P<0.05)。结论相比于舒芬太尼,盐酸纳布啡用于老年患者腹腔镜下胆囊切除术后镇痛,镇痛效果确切,可有效减少术后并发症的发生,缩短住院时间,值得临床重视并推广。

Objective To investigate the clinical effect of nalbuphine and sulfentanyl on analgesia after laparoscopic cholecystectomy in elderly patients. Methods 112 elderly patients who underwent laparoscopic cholecystectomy in our hospital from May 2017 to May 2018 were divided into two groups: The control group and the experimental group,and 56 cases in each group. The control group was given sulfentanyl for postoperative analgesia,while the experimental group was given nalbuphine hydrochloride for postoperative analgesia. The VAS pain score and sedation Ramsay score of the two groups were compared,and the incidence of postoperative nausea,vomiting and drowsiness in two groups were evaluated. Results The analgesic and sedative Ramsay scores of VAS in group B were lower than those in group A,the difference was statistically significant ( P < 0. 05);The incidence of clinical nausea,vomiting and drowsiness in group B were significantly lower than those in group A,the difference was statistically significant ( P < 0. 05);The length of stay in group B was significantly shorter than that in group A,the difference was statistically significant ( P < 0. 05 ). Conclusions Compared with sulfentanyl, nalbuphine is used for postoperative analgesia after laparoscopic cholecystectomy in elderly patients,Analgesic effect is accurate,can effectively reduce the occurrence of postoperative complications,shorten hospital stay,worthy of clinical attention and promotion.