动态对比增强磁共振在肿瘤预后预测中的研究进展

Advances in dynamic contrast-enhanced magnetic resonance imaging in predicting tumor prognosis

近些年来,在临床诊疗过程中,肿瘤性疾病的预后预测受到重视。而目前通过多模态磁共振成像对肿瘤疾病进行预后预测的研究有较多进展。动态对比增强磁共振作为多模态磁共振的一种,以肿瘤组织微血管系统灌注和渗透为基础,通过连续、快速的成像方法,获取注入对比剂前后的图像,结合半定量及定量分析,从微循环角度分析病变的微观情况,进而评价肿瘤的特征,在肿瘤性疾病的预后预测中得到颇多应用。作者就动态对比增强磁共振在肿瘤疾病预后预测中的研究进展进行综述,阐明其临床应用价值。

In recent years,the prognosis of neoplastic diseases has been paid attention to during clinical diagnosis and treatment.At present,there are many advances in the study of prognosis prediction of tumor diseases by multimodal magnetic resonance imaging.Dynamic contrast-enhanced magnetic resonance imaging is a kind of multi-modal magnetic resonance.It can be based on the perfusion and permeation of tumor tissue microvascular system.Through continuous and rapid imaging methods,images before and after injection of contrast agent can be obtained,combined with semi-quantitative and quantitative analysis.From the perspective of microcirculation,the microscopic condition of the lesion is analyzed,and the dynamic data analysis is carried out by quantitative or semi-quantitative methods.The characteristics of the tumor are evaluated from different aspects,and it has been widely used in the prognosis prediction of tumor diseases.In this paper,the research progress of dynamic contrast-enhanced magnetic resonance imaging in the prediction of tumor disease prognosis is reviewed,and its clinical application value is clarified.