单胃动物锌代谢及其对营养需要量和饲料锌生物利用率估算的影响（英文）

Zn metabolism of monogastric species and consequences for the definition of feeding requirements and the estimation of feed Zn bioavailability

矿物质营养研究的主要目标是为猪饲养者提供饲料锌利用率和总锌需要量信息,这些需要量信息受到饲养条件的影响.这只能通过应用精确实验模型来阐明锌代谢的基本原理.本综述总结了单胃动物体内锌稳态的最重要方面,包括锌的获取和排泄的分子机理,尤其强调骨骼以及外分泌胰腺在这种稳态调节中的作用.最后,文章讨论了上述生理学原理对试验设计产生的影响,旨在解决锌需要量和生物利用率的问题.

A major goal of mineral nutrition research is to provide information of feed zinc (Zn) utilization efficiency and gross Zn requirements as affected by changing rearing conditions. This can be achieved only by applying precise experimental models that acknowledge the basic principles of Zn metabolism. This review article summarizes the most important aspects of Zn homeostasis in monogastric species, including molecular aspects of Zn acquisition and excretion. Special emphasis is given to the role of the skeleton as well as the exocrine pancreas for animal Zn metabolism. Finally, we discuss consequences arising from these physiological principles for the experimental design of trials which aim to address questions of Zn requirements and bioavailability.