神经节细胞瘤的MSCT诊断价值

Application Value of MSCT in the Diagnosis of Ganglionneuroma

目的:探索神经节细胞瘤的MSCT诊断价值,以提高认识。方法:回顾性分析2010年4月1日到2018年4月30日之间经手术病理证实的51例神经节细胞瘤患者的临床及影像资料,所有患者均行CT平扫+增强扫描,记录患者的性别、年龄、临床症状、发病部位、大小、形态、密度、强化程度等情况,分析其相关性。结果:男性36例,女性15例,年龄为8 - 64岁,中位年龄为30.73 ± 14.46岁,小于35岁者36例,大于35岁者15例;27例有临床症状,24例无临床症状;发生于腹膜后39例,发生于其他部位(脊柱、纵隔)12例;30例直径> 5cm, 21例< 5cm,形态不规则21例,类圆形30例;48例均沿长轴生长;12例有伴随影像(血管受包绕、肋间隙增宽);钙化者15例;29例均为轻度强化,22例无强化。统计结果示:年龄与发病部位有统计学意义(χ2=6.538 , P<0.05),患者的发病部位与病灶大小(按照是否≥5cm)有统计学意义(χ2=7.412 , P<0.05);不同患者的发病部位与临床症状有统计学意义(χ2=4.917 , P<0.05),不同患者发病部位与性别有统计学意义(χ2=6.538, P<0.05);不同患者发病部位与伴随影像有统计学意义(χ2=6.111, P<0.05);不同患者病灶大小与强化程度有统计学意义(χ2=5.437, P<0.05);不同患者病灶形态与强化程度有统计学意义(χ2=5.126, P<0.05)。结论:神经节细胞瘤虽少见,但其具有一定的特征性,MSCT增强扫描具有很好的诊断价值。

Purpose: To study the value of MCST in the diagnosis of ganglionneuroma. Methods: The clinical features and imaging findings in 51 cases with ganglionneuroma, proved by surgery and pathology results were analyzed retrospectively from 1 April 2010 to 30 April 2018. All the cases were performed with and without contrast- enhanced scan, the clinical data of patients gender,age and the location, size, shape, density, enhancement degree of the ganglioneuroma were analyzed. Results: There were 36 males and 15 females aging from 8 to 64 years old. The median age was 30.73±14.46 years old. Of them 36 cases were younger than 35 years old and 15 cases were older than 35 years old. There were 27 cases with clinical symptoms and 24 cases with no clinical symptoms;39 cases occurred in the retroperitoneum and 12 cases occurred in the other parts (spine and mediastinum);30 cases were greater than or equal to 5 cm and 21 cases were less than 5 cm in diameter;21 cases were with irregular shape and 30 cases were with round shape;48 cases grew along the long axis of the body, 12 cases had accompanied features (vessel surrounded and widening of intercostal space);15 cases were with calcification;29 cases were with mild enhancement and 22 cases with no enhancement. The statistical result showed that the age and location were with statistically significant difference (χ2=6.538, P<0.05);the location and size (according to whether greater than or equal to 5 cm) were with significant difference χ2=7.412, P<0.05);the location and clinical symptoms were with significance (χ2=4.917, P<0.05);the location and sex were with statistical significance (χ2=6.538, P<0.05);the location and accompanying features were with statistical significance (χ2=6.111, P<0.05);the size of different patients and the degree of enhancement were with statistical significance (χ2=5.437,P<0.05);the lesion shape of different patients and degree of enhancement were with statistical significance (χ2=5.126, P<0.05).Conclusion: Ganglionneuroma is rare, but it is characteristic, the enhanced MSCT scan plays an important role in the diagnosis.