良性脊索细胞瘤影像探讨及文献回顾

Imaging and Literature Review of Benign Notochordal Cell Tumor

目的:研究良性脊索细胞瘤的CT和MRI征象。方法:收集2007年7月到2018年9月8例经手术病理证实的良性脊索细胞瘤的术前CT (8/8)、MRI (4/8)资料,男5例,女3例,平均年龄53.6岁。结果:位于颈椎5例,胸椎2例(其中1例为多发),腰椎1例。CT可见8例均有不同程度的椎体骨质增生硬化,其中5例硬化累及整个椎体;有2个病灶在硬化区内有小囊状低密度骨质破坏。4例在MRI上均呈T1WI低信号,T2WI高信号,病变内信号不均匀,病变周围未见高信号水肿,未见强化。结论:BNCT可以同时与其他多种恶性肿瘤共存,好发年龄与部位和脊索瘤相同,但CT±BNCT表现为整个椎体或后半椎体均匀的骨质增生硬化,因缺乏新生血管,MRI上无任何强化。

Purpose: To study the CT and MRI findings of benign notochordal cell tumor (BNCT). Methods: Preoperative CT (8/8) and MRI (4/8) data of 8 cases with BNCT confirmed by surgery and pathology results from July 2007 to September 2018 were collected, including 5 males and 3 females, with an average age of 53.6 years old. Results: Five cases were located in the cervical spine, 2 in the thoracic spine (1 of which was multiple), and 1 in the lumbar spine. CT showed different degrees of vertebral hyperostosis and sclerosis in 8 cases, among which 5 cases demonstrated sclerosis of the entire vertebral body. Two lesions showed small cystic bone destruction in the sclerotic area. All the 4 patients showed low intensity signal on T1WI and high intensity signal on T2WI, heterogeneous intensity signal inside the lesion, no high intensity signal edema around the lesion, and no enhancement. Conclusion: BNCT can coexist with a variety of other malignancies at the same time. The onset age and location of the BNCT are similar with chordoma. However, the BNCT shows homogeneous bone hyperostosis and sclerosis in the whole vertebral body or the posterior half of the vertebral body on the CT.