益生菌在代谢综合征中的潜在作用及研究进展

Potential role of probiotics in metabolic syndrome and its study advances

代谢综合征是一种代谢异常疾病,易引起高血糖、高血压、高血脂、动脉粥样硬化和血栓或炎症状态等,其发病率逐年提升,目前代谢综合征已成为世界性公共卫生问题。近来研究表明,该病的发生和进展与肠道菌群紧密相关。如何通过调节肠道菌群改善代谢综合征已成为目前的研究热点,益生菌作为一种对人体健康有益的活的微生物,可直接调节肠道菌群。越来越多的研究也显示益生菌具有改善代谢综合征的作用,然而也有部分人持中立或反对观点。该文综述了近几年来,代谢综合征及益生菌的相关研究进展,试图为代谢综合征提供一种有效的治疗方法,同时为益生菌进一步研发与利用提供参考。

Metabolic syndrome(MS)is a multimetabolic disorder,easily causes hyperglycemia,hypertension,arterial athrosclerosis,thrombus or inflammatory status,etc.,its incidence rate is increasing year by year.At present,MS has become a worldwide public health problem.The recent studies indicate that its occurrence and development are closely correlated with the intestinal bacterial flora.How to improve MS by regulating the intestinal flora has become the hot points of present study.Probiotics,as a living microorganism beneficial to human health,can directly regulate the intestinal flora.More and more studies have shown that probiotics possesses the role for improving MS,but some people take a neutral or opposing view.This article reviews the related study advances in MS and probiotics during the recent years,and tries to provide an effective treatment method for MS,and at the same time provide reference for the further study and utilization of probiotics.