舌鳞状细胞癌颈淋巴结转移特点及临床治疗

Characteristics and clinical treatment of cervical lymph node metastasis in tongue squamous cells

目的分析舌鳞状细胞癌颈淋巴结转移的临床特点。方法选取2016年3月至2018年7月本院收治的53例舌鳞状细胞癌患者,采用回顾性分析法,评估舌鳞状细胞癌颈淋巴结转移特点,且对颈淋巴结转移的相关因素进行分析。结果53例患者在病灶最大直径及肿瘤细胞分化程度方面对比差异无统计学意义;两组患者浸润方式、组织学恶性度分级方面对比差异具有统计学意义(P<0.05)。浸润方式、组织学恶性度分级均是导致舌鳞状细胞癌颈淋巴结转移的单独危险因素。结论舌鳞状细胞癌颈淋巴结转移的危险因素在于浸润方式及组织学恶性度分级;应在早期实施原发病灶切除术的同时给予颈淋巴结清扫术治疗,因为该病灶组织早期存在较高的隐匿性颈淋巴结转移率。

Objective Analysis of the clinical features of cervical lymph node metastasis in tongue squamous cells. Methods 53 patients with tongue squamous cell carcinoma admitted to our hospital from March 2016 to July 2018. Retrospective analysis was used to evaluate the characteristics of cervical lymph node metastasis and analyze the related factors of cervical lymph node metastasis. Results There was no significant difference in the maximum diameter of the lesion and the degree of differentiation of tumor cells in 53 patients, but there were significant differences in the invasion mode and histological malignancy classification (P<0.05). However, there were significant differences in the classification of infiltration mode and histological malignancy (P<0.05). Infiltration pattern and histological malignancy grading were independent risk factors for cervical lymph node metastasis in tongue squamous cell carcinoma. Conclusion Risk factors for cervical lymph node metastasis in tongue squamous cells are infiltration pattern and histologic severity classification;Cervical lymph node dissection should be performed at the same time as the primary lesion resection is performed at an early stage, because there is a high rate of occult cervical lymph node metastasis in the tissue of the lesion.