红细胞分布宽度与心血管疾病关系的研究进展

Research Progress in Relationship between Red Blood Cell Distribution Width and Cardiovascular Disease

在临床血常规的检测中,红细胞分布宽度(RDW)具有重要意义,可反映外周循环血液中红细胞变异性,以往多用于不同类型的贫血诊断及鉴别诊断。近年来,人们发现RDW对急性冠状动脉综合征、心房颤动、心力衰竭、高血压、肺动脉高压、外周血管疾病、缺血性脑病等疾病的发生发展、严重程度、并发症及预后具有预测价值,且与一些心脏手术(射频消融术、冠状动脉旁路移植术、瓣膜术等)的预后也具有相关性。未来,RDW有望成为一种预测心血管疾病的标志物,进而在临床广泛应用。

Red blood cell distribution width(RDW) plays an important role in clinical routine blood test.It can reflect the variability of red blood cells in peripheral circulation.It has been used in the diagnosis and differential diagnosis of different types of anemia in the past.In recent years,it has been found that RDW has predictive value for the development,severity,complications and prognosis of acute coronary syndrome,atrial fibrillation,heart failure,hypertension,pulmonary hypertension,peripheral vascular disease,ischemic encephalopathy,etc.,and is also relevant to the prognosis of some cardiac procedures(radiofrequency ablation,coronary artery bypass grafting,valvuloplasty,etc.).In the future,RDW is expected to become a predictor of cardiovascular disease and be widely used in clinical practice.