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分子靶向药物治疗脑胶质瘤的研究 被引量:2

Molecular targeted drug therapy for glioma
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摘要 IDH(柠檬酸脱氢酶同工酶)突变、免疫治疗、表观遗传学、表皮生长因子受体三型突变、表皮生长因子受体、抗血管生成以及其他类型的分子靶向药物是未来对胶质瘤治疗的相关可行方案,贝伐珠单抗在GBM(复发神经胶质母细胞瘤)的治疗中应用,可取得对应的效果。对于GBM患者,在其放化疗的过程中,实施尼妥珠单抗治疗,有望取得一定的效果。 IDH mutation(citric acid dehydrogenase isozyme),immunotherapy,epigenetics,epidermal growth factor receptor type three mutations,epidermal growth factor receptor,anti-angiogenesis and other types of molecular targeted drugs are feasible solutions related to the future for the treatment of gliomas,beacizumab bead sheet resistance in GBM neurological glioblastoma(recurrence)in the treatment of application,the corresponding effect can be obtained.For patients with GBM,in the course of chemoradiotherapy,treatment with nituzumab is expected to achieve a certain effect.
作者 王朝翔 王震宇 倪兰春 Wang Chaoxiang;Wang Zhenyu;Ni Lanchun(Department of Neurosurgery,Affiliated Hospital of Nantong university,Nantong,Jiangsu,226000,China)
出处 《当代医学》 2019年第22期190-192,共3页 Contemporary Medicine
关键词 分析靶向药物 脑胶质瘤 研究分析 Analysis of targeted drugs Glioma Research and analysis
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