摘要
甲基苯丙胺(METH)是全球滥用最广泛的毒品之一,严重危害人类身心健康。该研究基于石墨烯、壳聚糖复合膜修饰玻碳电极(RGO/CHIT/GCE),采用示差脉冲伏安法,简单、快速地测定生物样本中的甲基苯丙胺。该方法具有较高的检测灵敏度,在+1.28V出现明显的甲基苯丙胺的氧化峰,响应峰电流i(μA)与METH浓度的对数(logc)在6.0×10^-9-8.0×10^-5mol/L范围内呈良好的线性关系,检出限可达2.0×10^-9mol/L。同时具有良好的稳定性和抗干扰能力,有望为甲基苯丙胺的灵敏快速检测提供一种新方法。
Methamphetamine is one of the most widely abused drugs in the world, which is seriously harmful to the human health. In this study, a simple, rapid DPV method for the determination of methamphetamine in biological samples was established by graphene and chitosan inorganic/organic composite film modified glassy carbon electrode. The method has high sensitivity, and the apparent oxidation peak of methamphetamine appeared at +1.28 V. A good linearity was obtained in the range of 6.0×10^-9-8.0×10^-5mol/L with the detection limit of 2.0×10^-9mol/L. Stability and anti -interference ability were excellent. The study also expects to provide a new idea for rapid detection of methamphetamine.
作者
白慧萍
张瑞林
付开心
赵康宏
张艮林
Bai Hui-ping;Zhang Rui-lin;Fu Kai-xin;Zhao Kang-hong;Zhang Gen-lin(Yunnan University,Kunming 650091,China;Institut of Forensic Medical,Kunming Medical University,Kunming 650050,China)
出处
《化学传感器》
CAS
2018年第3期60-66,共7页
Chemical Sensors
基金
云南省教育厅科学基金(Nos.2017ZZX231,2018JS005)
云南省科技厅-昆明医科大学应用基础研究联合专项(No.2017FE468)资助
关键词
甲基苯丙胺
石墨烯
电化学氧化
示差脉冲伏安法
methylamphetamine
graphene
electrochemical oxidation
differential pulse voltammetry
