脑梗死确诊后3个月抑郁发病相关因素研究

Study on Related Factors of Depression in 3 Months after Diagnosis of Cerebral Infarction

目的探究脑梗死确诊后3个月抑郁发病相关因素。方法该院神内科2017年12月-2018年7月期间收治脑梗死患者86例,其中43例患者于发病3个月内并发抑郁症。将未并发抑郁症的患者作为对照组,其余43例为观察组,探究两组异同并分析致病原因。结果观察组1~3月发病、高血压、冠心病、合并感染例数分别为31例、31例、33例、29例,多于对照组,差异有统计学意义(χ^2=9.241、32.298、36.965、25.487,P<0.05)。Pearson分析发病时间、高血压及冠心病史、发病合并感染与脑梗死确诊3个月内抑郁发作存在明显相关性(P<0.05)。Logistic分析1~3月发病、有高血压史、有冠心病史、发病后合并感染为脑梗死确诊后3个月抑郁发病的危险因素。结论脑梗死中1~3月发病、存在高血压、冠心病病史、梗死期间合并感染的患者确诊3个月内易出现抑郁犯病,故需加强警惕。

Objective To explore the related factors of depression in the three months after the diagnosis of cerebral infarction. Methods A total of 86 cases with cerebral infarction were enrolled in the Department of Internal Medicine from December 2017 to July 2018, of which 43 cases developed depression within three months of onset. The patients with no concurrent depression were used as the control group, and the remaining 43 cases were in the observation group. The similarities and differences between the two groups were explored and the cause of the disease was analyzed. Results The incidence of hypertension, coronary heart disease, and co-infection in the observation group from January to March was 31 cases, 31 cases, 33 cases, and 29 cases, respectively, which was more than the control group. The difference was statistically significant(χ^2=9.241, 32.298, 36.965, 25.487, P<0.05). Pearson analysis showed that the onset time, hypertension and coronary heart disease history, combined infection and cerebral infarction were significantly correlated with depressive episodes within 3 months (P<0.05). Logistic analysis of the incidence of hypertension from 1 to 3 months, history of hypertension, history of coronary heart disease, and infection after onset were the risk factors for depression after three months of diagnosis of cerebral infarction. Conclusion Patients with cerebral infarction from 1 to 3 months, with hypertension, history of coronary heart disease, and co-infection during infarction are diagnosed with depression and illness within 3 months. Therefore, it is necessary to be vigilant.