多学科综合治疗:不可切除胸段局部进展期食管鳞癌的治疗现状和未来

Multidisciplinary team: the present and advance of unresectable locally advanced thoracic esophageal squamous carcinoma

中国是食管癌的高发地区。对于不可切除局部进展期食管癌,如何进一步增加治愈机会并提高远期生存,是国内外肿瘤医师共同关注的临床难题。近年来越来越多的临床研究在同步放化疗、诱导化疗及其后续治疗等治疗方面进行探索,本文主要对不可切除胸段局部进展期食管鳞癌提出的治疗策略予以阐述和比较,以期为临床实践中的选择提供依据。

There is a high incidence of esophageal cancer in China.Unresectable locally advanced thoracic esophageal carcinoma are very lethal diseases.To further increase the disease control and improve the survival based on multidisciplinary treatment are great challenges to the oncologists all over the world.Recently,an increasing number of clinical trials are reported focusing on concurrent chemo radiotherapy,induction chemotherapy and subsequent treatment.This article reviewed the strategies of treatment for unresectable locally advanced thoracic esophageal squamous carcinoma,to provide reasonable evidence for wise option for treatment of this disease.