1例原发性肝癌合并2型糖尿病行射频消融术治疗后并发肝脓肿的药学监护

Pharmacological monitoring in a case of primary hepatocellular carcinoma with type 2 diabetes mellitus followed by hepatic abscess after radiofrequency ablation

目的 探讨原发性肝癌合并2型糖尿病行射频消融术治疗后并发肝脓肿的药学监护。方法 临床药师、护士与医生配合,对1例原发性肝癌合并2型糖尿病行射频消融术治疗后并发肝脓肿患者实施药学监护。通过对肝肾功能监护调整药物、按血培养结果调整抗生素、严密监测血压血糖等措施,在分析疾病、提供用药方案、监护药物不良反应及相互作用等方面提供药学服务。结果 在治疗过程中,感染病情得到控制,肝肾功能恢复正常,未出现药物不良反应,患者31 d后肝脓肿治愈出院。结论 实施药学监护对原发性肝癌合并2型糖尿病行射频消融术治疗后并发肝脓肿患者的抗菌治疗起到了积极作用。

Objective To investigate the pharmacological monitoring in a hepatic abscess patient after radiofrequency ablation for primary hepatocellular carcinoma with type 2 diabetes mellitus. Methods The patient’s liver and kidney function were monitored to tailor the medication regimen.The antibiotic therapy was adjusted based on the blood culture results.Blood pressure and blood sugar were also closely monitored.Pharmaceutical care is provided based on the diseases progress,the optimization of drug regimens,the monitoring of adverse drug reactions and interactions. Results In the course of treatment,no adverse drug reactions occurred.The infection was under control and the liver and kidney function returned to normal.The patient was recovered and discharged after 31 days of hospital stay. Conclusion Pharmaceutical care plays an active role in the antibiotic treatment for the seriously infected patients.