摘要
随着科研技术的不断发展和检测手段的不断进步,支链氨基酸(BCAAs)越来越多的被发现在2型糖尿病(T2DM)中发挥着重要的作用,影响着2型糖尿病患者的病情发展。支链氨基酸包括亮氨酸(Leu),异亮氨酸(Ile)和缬氨酸(Val),其代谢过程与2型糖尿病病情发展的相互影响机制尚不明确。这篇综述的目的是介绍支链氨基酸代谢与2型糖尿病的相关性并对国内外现存的各种关于支链氨基酸代谢与2型糖尿病的相互作用可能机制推测的总结,可有助于开发新型有效的2型糖尿病的疗法。
Nowadays,with the continuous development of scientific research technology and the continuous progress of testing methods,Branched chain amino acids (BCAAs) are found to be playing an increasingly important role in type 2 diabetes mellitus (T2DM),affecting the development of type 2 diabetes.Branched-chain amino acids include leucine,isoleucine and valine,and the mechanism of their influence on the development of type 2 diabetes remains unclear.The purpose of this review is to introduce the correlation between branched-chain amino acid metabolism and type 2 diabetes mellitus,and to provide a summary of the possible mechanisms of the interaction between branch chain amino acid metabolism and type 2 diabetes mellitus at home and abroad.It can help develop new and effective treatments for type 2 diabetes.
作者
张起维
黄鹤
Zhang Qiwei;Huang He(Department of Gastrointestinal Surgery,First Affiliated Hospital of Wannan Medical College,Wuhu 241000 China)
出处
《锦州医科大学学报》
CAS
2019年第4期103-106,共4页
Journal of Jinzhou Medical University
基金
安徽高校省级自然科学计划项目,项目编号:KJ2016A717
芜湖市科技计划重点项目,项目编号:2014hm27
关键词
支链氨基酸
2型糖尿病
胰岛素抵抗
Branched Chain Amino Acid
type-2 diabetes
insulin resistance