酶促合成烷基糖苷

Enzymatic synthesis of alkyl glycosides

综述了生物法合成烷基糖苷,包括糖苷酶选择、酶促糖苷化、烷基糖苷的酶促合成等几个方面。与传统化学合成法相比,烷基糖苷的酶促合成提供了极好的环保升级替代方案,具有较大的利用潜能和广阔前景。未来烷基糖苷的酶促合成可以通过开发新型基因工程菌,采用全细胞催化的方法,进行工业化放大研究。

The biological synthesis of alkyl glycosides, including glycosidase selection, enzymatic glycosidation, enzymatic synthesis of alkyl glycosides, were reviewed. Compared with conventional chemical synthesis methods, enzymatic synthesis of alkyl glycosides provides an excellent alternative to environmental protection upgrading, and has great potential for exploitation and broad prospects. The enzymatic synthesis of alkyl glycosides in the future can be industrialized by the development of new genetic engineering enzymes using whole-cell catalysis.