微波消融术治疗血钙正常的原发性甲状旁腺功能亢进(NPHPT)老年患者1例

Microwave ablation for normocalcemic primary hyperparathyroidism (NPHPT) in an elderly patient

血钙正常的原发性甲状旁腺功能亢进(normocalcemic primary hyperparathyroidism,NPHPT)是原发性甲状旁腺功能亢进(PHPT)的一种特殊类型,是指血钙水平持续正常,而血甲状旁腺激素(parathyroid hormone,PTH)水平升高,同时需除外继发性甲状旁腺功能亢进的因素。NPHPT发病机制、临床表现、自然进程及转归尚不清楚,治疗存在争议,首选手术治疗,但对于不能或不愿手术治疗的患者尚无统一意见,本文报道1例2017年7月行微波消融术治疗NPHPT老年患者,术后患者临床症状及PTH水平基本缓解。微波消融对于不愿手术的老年PHPT患者有一定的应用前景。

Normocalcemic primary hyperparathyroidism (NPHPT) is a special type of primary hyperparathyroidism (PHPT).It means that the level of serum calcium remains normal,while the level of serum parathyroid hormone (PTH) is elevated.At present,Because its pathogenesis,clinical manifestations,natural process and outcome are still unclear,there are some disputes on its treatment.Currently,surgical treatment is recommended,but there is no consensus on those who are unable or unwilling to receive surgical treatment.This paper reports a NPHPT case treated by microwave ablation in Jul.,2017.The clinical symptoms and hormones of parathyroid gland were basically relieved after operation.Microwave ablation has a certain application prospect for elderly patients with NPHPT who do not want to surgery.