自体脂肪干细胞的浓缩提取及在面部填充中的应用效果

The Concentrated Extraction of Autologous Adipose Stem Cells and its Application Effect in Facial Filling

目的:探讨自体脂肪干细胞的浓缩提取技巧及在面部填充治疗中的远期效果和安全性。方法:2013年-2017年对38例颜面部凹陷或组织缺容的就医者行自体脂肪干细胞移植填充矫治,术后随访评价矫治效果。结果:38例就医者中,有33例接受了1次自体脂肪干细胞移植,5例进行了再次自体脂肪干细胞移植。术后随访时间为3~41个月,术后颜面部缺容及轮廓欠佳现象获得显著改善。未出现局部硬结、皮肤表面不平整、注射针孔瘢痕及色素沉着等不良反应。术后就医者和医师对效果的总有效率评价分别为94.7%和97.4%。结论:自体脂肪干细胞移植是一种安全、远期疗效理想的面部年轻化治疗方式,严格遵照医疗规范及实验室提取脂肪干细胞的提取方法操作,可以有效提高脂肪干细胞的移植成活率。

Objective To explore the concentrated extraction technique of autologous adipose stem cells and its long-term effect and safety in the treatment of facial filling.Methods From 2013 to 2017,38 patients with facial depression or tissue deficiency were treated with autologous adipose stem cell transplantation.The effect of the treatment was evaluated after follow-up.Results Among 38 patients,33 cases received one autologous adipose stem cell transplantation and 5 cases received another autologous adipose stem cell transplantation.The follow-up period was 3 to 41 months,and the facial deficiency and poor contour were significantly improved.No adverse reactions such as local sclerosis,skin surface irregularity,pinhole scar and pigmentation were found.The total effective rate of the patients and doctors after operation was 94.7%and 97.4%respectively.Conclusion Autologous adipose stem cell transplantation is a safe and long-term ideal treatment for facial rejuvenation.Strict compliance with medical standards and laboratory extraction methods of adipose stem cells can effectively improve the survival rate of adipose stem cell transplantation.