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福多司坦联合纤支镜灌洗治疗老年重症肺部感染的疗效 被引量:13

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摘要 目的探讨福多司坦联合纤维支气管镜灌洗治疗老年重症肺部感染的疗效及其临床应用价值。方法重症肺部感染患者132例,按治疗方法不同分为对照组、福多司坦组、灌洗组、联合灌洗组,四组患者均接受肺部感染常规治疗,福多司坦组口服福多司坦,灌洗组进行纤支镜肺段灌洗,联合灌洗组口服福多司坦联合纤支镜肺段灌洗。比较治疗前后各组患者治疗效果,临床症状与体征缓解时间、血气分析、白细胞计数与降钙素原(PCT)水平和不良反应与并发症发生率。结果联合灌洗组的临床症状和体征缓解时间较对照组、福多司坦组和灌洗组明显缩短(P<0.01);联合灌洗组患者动脉血氧分压(PaO2)和血氧饱和度(SaO2)较对照组、福多司坦组和灌洗组明显升高,二氧化碳分压(PaCO2)显著降低(P<0.01);联合灌洗组患者血液白细胞和PCT水平较对照组、福多司坦组和灌洗组明显降低(P<0.01);联合灌洗组总有效率明显高于灌洗组,不良反应和并发症发生率明显低于对照组、福多司坦组和灌洗组(P<0.05)。结论福多司坦联合纤支镜灌洗治疗重症肺部感染的效果显著,有效避免严重并发症的发生。
作者 郑敏辉 邱琴
出处 《中国老年学杂志》 CAS 北大核心 2019年第15期3674-3677,共4页 Chinese Journal of Gerontology
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