RDW与55岁以上急性胰腺炎患者病情严重程度及预后的相关性

Correlations between RDW and the severity and prognosis of acute pancreatitis patients over 55 years old

目的:探讨红细胞体积分布宽度(RDW)与55岁以上急性胰腺炎(AP)患者病情严重程度及预后的相关性。方法:选取96例55岁以上AP患者,分为轻症急性胰腺炎组(MAP组,56例)和重症急性胰腺炎(SAP组,40例),分别在入院第1 d、治疗第3 d和治疗第7 d检测两组患者的RDW和血清CRP水平,并同期计算两组患者APACHE-Ⅱ评分。结果:不同病情和时间的交互作用对RDW、CRP和APACHE-Ⅱ评分的影响具有统计学意义(均P<0.01);两组患者的RDW、CRP和APACHE-Ⅱ评分具有随时间变化的趋势(均P<0.05);MAP组患者的RDW、CRP和APACHE-Ⅱ评分显著低于SAP组(均P<0.01);SAP组中存活组患者的RDW、CRP和APACHE-Ⅱ评分显著低于死亡组(均P<0.01);RDW与CRP、APACHE-Ⅱ评分呈正相关(均P<0.05)。结论:RDW能够判断55岁以上AP患者的病情严重程度及预后。

Objective:To investigate the correlations between erythrocyte volume distribution width(RDW) and the severity and prognosis of acute pancreatitis(AP) patients over 55 years old.Methods:96 patients over 55 years old with AP were divided into mild acute pancreatitis group(MAP group, 56 cases) and severe acute pancreatitis group(SAP group, 40 cases). The levels of RDW and serum CRP were measured on the first day of admission, the third day of treatment and the seventh day of treatment, and the APACHE-Ⅱ scores of the two groups were calculated at the same time.Results:The interaction of different conditions and time had significant influence on RDW, CRP and APACHEE-Ⅱ scores(all P<0.01);the RDW, CRP and APACHEE-Ⅱ scores of the two groups had a tendency to change with time(all P<0.05);the RDW, CRP and APACHEE-Ⅱ scores of the MAP group were significantly lower than those of the SAP group(all P<0.01). The scores of RDW, CRP and APACHEE-Ⅱ in survival group were significantly lower than those in death group(all P<0.01). RDW was positively correlated with CRP and APACHE-Ⅱ scores(all P<0.05).Conclusion:RDW can judge the severity and prognosis of AP patients over 55 years old.