氯吡格雷联合阿司匹林治疗短暂性脑缺血发作

Therapeutic Effect of Clopidogrel Combined With Aspirin on Transient Ischemic Attack

目的观察氯吡格雷联合阿司匹林治疗短暂性脑缺血发作的临床疗效.方法选取2017年1月-2018年6月因短暂性脑缺血发作在我院就诊的92例患者作为研究对象,将其随机分为两组.对照组采用阿司匹林治疗,观察组采用氯吡格雷联合阿司匹林治疗,对比两组患者的疗效,治疗前后两组患者血流动力学改善情况及不良反应发生情况.结果观察组患者的治疗有效率为95.65%,高于对照组的76.09%,且观察组患者的血流动力学检查指标优于对照组,组间各数据比较,差异均有统计学意义(P<0.05).对照组患者的不良反应发生率为10.87%,较观察组的8.70%高,但组间数据比较,差异无统计学意义(P>0.05).结论短暂性脑缺血发作时采用氯吡格雷联合阿司匹林进行治疗可改善患者临床症状.

Objective To observe the effect of clopidogrel combined with aspirin in the treatment of transient ischemic attack effect. Methods From January 2017 to June 2018, 92 patients who were hospitalized in our hospital for transient ischemic attack were selected as the study objects, and they were randomly divided into two groups. The control group was treated with aspirin, and the observation group was treated with clopidogrel combined with aspirin. The effective rate, hemodynamic improvement and adverse reactions occurred before and after treatment was compared. Results The effective rate of the observation group was 95.65%, which was higher than 76.09% of the control group. The hemodynamic indexes of the observation group were better than those of the control group. There were significant differences in the data between the two groups (P < 0.05). The incidence of adverse reactions in the control group was 10.87%, which was higher than that in the observation group (8.70%), but there was no significant difference between the two groups (P > 0.05). Conclusion Clopidogrel combined with aspirin can improve the clinical symptoms of patients with transient ischemic attack.