影像引导在胶质瘤导航手术中的应用与研究进展

The application and research progress of image guidance in navigation surgery for glioma

胶质瘤的手术切除原则是在保存重要神经功能的前提下尽可能多地切除肿瘤以减少复发率,但术中肉眼识别肿瘤边界较为困难,而影像引导技术在辅助外科胶质瘤手术中通过实时成像有助于保护神经、提高肿瘤切除率和改善病人预后情况。现就CT、MRI、多模态影像技术、荧光影像导航技术、新材料及靶向探针在胶质瘤手术中的临床应用、优势和局限性,以及研究进展进行综述。

The principle in glioma surgery is to resect as many tumors as possible to reduce the recurrence rate while preserving the important nerve function, but it is difficult to identify the boundary of the tumors with the naked eye during the operation. Image-guided technology by real-time imaging can help to protect the nerves, improve the resection rate of the tumors, and improve the prognosis of the patients in assisted surgery of glioma. This article reviews the clinical applications, advantages, limitations, and research progress of CT, MRI, multi-modal imaging technology, fluorescent imaging navigation technology, new materials and targeted probes in glioma surgery.