应用脱细胞异体真皮补片行阴茎增粗术的并发症及处理

Complications and management for penile augmentation with acellular dermal matrix

目的:探讨应用脱细胞异体真皮补片行阴茎增粗术的术后并发症及其相关处理。方法:回顾性分析2016年6月至2019年1月于北京大学人民医院及外院会诊收治的78例应用脱细胞异体真皮补片行阴茎增粗术患者的临床资料,对术后并发症进行总结并提出相应解决方案。结果:本组78名患者平均年龄31.14岁(21~66岁),均应用脱细胞异体真皮补片行阴茎增粗术,随访时间3~34个月,术后3个月随访时周长平均增加1.1cm(0.5~2.1cm),平均随访时间12.20个月。术后并发症包括:勃起不适感47例、伤口愈合不良12例、增粗效果不明显10例、补片邮票样改变9例、伤口周围血肿8例、包皮水肿7例、伤口感染4例、背侧皮肤坏死3例、心理影响2例,予以相应治疗后最终7名患者行补片取出术。结论:规范的手术方法、严谨的术后护理以及对患者的充分告知可以有效减少应用脱细胞异体真皮补片行阴茎增粗术的并发症,对并发症进行及时且正确的处理可以获得满意的效果。

Objective: To investigate and analyze the complications of penile augmentation with acellular dermal matrix (ADM) and following management. Methods: This was a retrospective review of all patients who received penile augmentation with ADM between June 2016 and January 2019. The patients were evaluated with outpatient physical examination. Related complications and following management were summarized and analyzed. Results: Between June 2016 and January 2019, ADM was used as filling material on 78 patients (mean age: 31.14 years, range: 21-66 years), who were successfully received penile augmentation surgery. In the follow-up three months, the penile circumference was increased by 1.1 cm (0.5-2.1 cm) on average. The mean follow-up time was 12.20 months. In this study, there were 47 (60.26%, 47/78) patients with erectile discomfort, 91.49%(43/47) of whom manifested as erectile traction. There were 12 (15.38%, 12/78) patients with delayed healing, improved by daily regular dressing change. There were 10 (12.82%, 10/78) patients with unobvious augmentation effect. There were 9 (11.54%, 9/78) patients with stamp-like changes of ADM. There were 8 (10.26%, 8/78 ) patients with wound hematoma and 7 (8.97%, 7/78) patients with foreskin edema, relieved by compression with wrap. There were 4 (5.13%, 4/78) patients with wound infection and 3 (3.85%, 3/78 ) patients with skin necrosis of the dorsal side, which could be treated with ADM removal and repair surgery with bipedicle scrotal flap. And there were 2 (2.56%, 2/78) patients suffering psychological influence. Finally, most patients with various complications recovered successfully, however 7 patients ( 8.97%, 7/78) underwent ADM removal surgery. Conclusion: Using ADM as filling material could achieve positive effect in penile augmentation but the complications are common and cannot be neglected. Standardized surgical methods, rigorous postoperative care, and adequate notification with patients can effectively reduce the complications of penile augmentation with ADM. To treat properly and timely for complications can obtain satisfactory results.