沙丁胺醇联合布地奈德治疗小儿哮喘发作的效果

The Effect of Salbutamol Combined With Budesonide on Asthma Attack in Children

目的分析沙丁胺醇联合布地奈德在治疗小儿哮喘急性发作方面的临床治疗效果。方法选择我院于2016年6月-2018年6月收治的68例小儿哮喘急性发作期患儿作为本次研究对象,并将其划分为观察组与对照组,每组各34例。对照组患儿行常规治疗方案,观察组患儿在常规治疗方案的基础上,采用沙丁胺醇联合布地奈德治疗。比较两组患儿治疗后的临床疗效和肺功能变化情况,判断治疗方案的有效性。结果治疗有效率方面,观察组患者的治疗有效率为94.1%,而对照组患者的治疗有效率为79.4%,组间数据比较,差异具有统计学意义(χ^2=5.620,P=0.005);肺功能方面,观察组在治疗后的FEV1、FVC、VC、PEFR指标均优于对照组,组间数据比较,差异具有统计学意义(P<0.05)。结论沙丁胺醇联合布地奈德在治疗小儿哮喘急性发作方面效果显著,症状可快速消失,肺功能明显改善,对于预防气道炎症的产生与不良反应的控制都能起到良好的促进作用,是治疗的合理方案选择。

Objective To analyze the clinical efficacy of albuterol combined with budesonide in the treatment of acute asthma attacks in children.Methods 68 cases of children with acute asthma in our hospital from June2016 to June 2018 were selected as study objects,and were divided into observation group and control group,34 cases in each group.The children in the control group were treated with conventional treatment regimen,and the children in the observation group were treated with albuterol combined with budesonide on the basis of conventional treatment regimen.The clinical efficacy and pulmonary function changes of the two groups were compared to determine the effectiveness of the treatment regimen.Results In terms of treatment efficiency,the treatment efficiency of the observation group was 94.1%,while that of the control group was 79.4%.There was a significant difference between the two groups(χ^2=5.620,P=0.005).In terms of lung function,the FEV1,FVC,VC and PEFR indexes of the observation group were better than those of the control group after treatment,and there was a significant difference between the two groups(P<0.05).Conclusion Albuterol combined with budesonide has a significant effect on the treatment of acute asthma in children,with symptoms rapidly disappeared and lung function significantly improved.It can play a good role in promoting the prevention of airway inflammation and the control of adverse reactions,and is a reasonable choice of treatment.