双胎妊娠自发性早产预防措施的研究进展

Progress in Preventive Measures for Spontaneous Preterm Birth in Twin Pregnancy

自发性早产是影响围产儿预后的主要原因之一。双胎妊娠的早产发生率明显高于单胎,确切的发病机制尚不明确。国内外对预防双胎妊娠自发性早产的预防措施尚无相关指南,早产的预防与治疗是预防双胎妊娠自发性早产的唯一方法。本研究就使用孕酮、子宫颈环扎术、宫缩抑制剂、子宫颈托、卧床休息等方法预防自发性早产进行阐述分析,以期为相关适应证的双胎妊娠采取相应的预防措施提供参考依据。

Spontaneous preterm birth is one of the main factors affecting the prognosis of perinatal infants.The preterm birth rate of twin pregnancy is significantly higher than the single births,and the exact pathogenesis is still unclear.There are no guidelines for prevention of spontaneous preterm birth in twin pregnancies now.Prevention and treatment of preterm birth is the only way to prevent spontaneous preterm birth in twin pregnancies.In this study,the use of progesterone,cervical cerclage,tocolytics,cervical support,bed rest and other methods to prevent spontaneous preterm birth were analysed,which provide reference for related indications of twin pregnancy to take appropriate preventive measures.