胃大部分切除术与单纯修补术治疗急性胃穿孔的疗效对比

Comparison on the Curative Effects of Subtotal Gastrectomy and Simple Repair in the Treatment of Acute Gastric Perforation

目的比较胃大部分切除术与单纯修补术治疗急性胃穿孔的疗效。方法选取2017年7月至2018年12月我院收治的急性胃穿孔患者72例,随机分为两组各36例。对照组患者采用胃大部分切除术治疗,观察组患者采用单纯修补术治疗。比较两组的临床相关指标,胃肠激素和胃蛋白酶水平,以及并发症。结果观察组的手术时间、住院时间及肛门排气时间均显著短于对照组,术中出血量显著少于对照组,差异均具有统计学意义(P<0.05)。术后,观察组的血管活性肠肽(VIP)、胃泌素(GAS)、胃蛋白酶原Ⅰ(PGⅠ)及PGⅡ水平均显著高于对照组,并发症发生率显著低于对照组,差异均具有统计学意义(P<0.05)。结论单纯修补术可有效恢复急性胃穿孔患者的胃肠功能,患者术中出血量少,术后恢复时间短,并发症发生率低。

Objective To compare the curative effects of subtotal gastrectomy and simple repair in the treatment of acute gastric perforation. Methods 72 patients with acute gastric perforation admitted to our hospital from July 2017 to December 2018 were selected and randomly divided into the two groups, with 36 cases in each group. The control group was treated with subtotal gastrectomy, and the observation group was treated with simple repair. The relevant clinical indicators, levels of gastrointestinal hormones and pepsin, and complications were compared between the two groups. Results The operation time, hospitalization time and anal exhaust time of the observation group were significantly shorter than those of the control group, and the intraoperative blood loss was significantly less than that of the control group(P <0.05). After surgery, the levels of vasoactive intestinal peptide(VIP), gastrin(GAS), pepsinogenⅠ(PGⅠ) and PGⅡ of the observation group were significantly higher than those of the control group, and the incidence of complications was significantly lower than that of the control group(P <0.05). Conclusions Simple repair can effectively restore the gastrointestinal function of patients with acute gastric perforation, with low intraoperative blood loss, short recovery time and low incidence of complications.