影响血管造影术后急性肾损伤的危险因素分析

Analysis on Risk Factors Affecting Acute Kidney Injury After Angiography

目的探讨分析影响血管造影术后急性肾损伤的危险因素。方法回顾性分析100例行血管造影术患者的临床资料,依据术后是否发生急性肾损伤分为对比剂肾病(CIN)组和对照组,比较两组的一般临床资料,采用多因素Logistic回归分析血管造影术后急性肾损伤的危险因素。结果100例患者中,22例(22.00%)出现急性肾损伤;两组在年龄、合并症(糖尿病、高血压、高血脂)、术前肌酐水平、术前运用心血管药物及肾功能情况方面具有显著差异(P<0.05);Logistic回归分析结果显示,年龄、合并症、术前运用心血管药物及肾功能不全均是血管造影术后急性肾损伤的危险因素。结论血管造影术后发生急性肾损伤与年龄、合并症、术前运用心血管药物及肾功能不全等均密切相关,临床应进行术前危险性预判并进行针对性防治。

Objective To explore and analyze the risk factors affecting acute kidney injury after angiography. Methods The clinical data of 100 patients undergoing angiography were retrospectively analyzed. The patients were divided into contrast-induced nephropathy(CIN) group and control group according to the occurrence of acute renal injury after operation. General clinical data were compared between the two groups, and multivariate Logistic regression analysis was used to analyze the risk factors for acute kidney injury after angiography. Results Of the 100 patients undergoing angiography, 22 cases(22.00%) had acute renal injury. Significant difference was found between the two groups in the aspects of age, complications(diabetes, hypertension, hyperlipidemia), preoperative creatinine level,preoperative use of cardiovascular drugs and renal function(P <0.05). Logistic regression analysis showed that age, complications, preoperative use of cardiovascular drugs and renal insufficiency were risk factors for acute kidney injury after angiography. Conclusions Acute kidney injury after angiography is closely related to age, complications, preoperative use of cardiovascular drugs and renal insufficiency.Preoperative risk prediction and targeted prevention should be carried out in clinic.