超声三维体积分析软件技术评估功能性消化不良小儿胃排空功能的临床价值

Clinical value of three - dimensional ultrasound VOCAL in evaluation of gastric emptying function in children with functional dyspepsia

目的探讨三维超声三维体积分析软件技术(VOCAL)评估小儿功能性消化不良(FD)的胃排空功能的临床价值.方法选取2018年1-6月在温州市中西医结合医院就诊的功能性消化不良患儿71例为研究对象(观察组),并选择无功能性消化不良症状的健康小儿71例为对照(对照组),对两组患儿不同时间段胃排空情况、胃窦幽门协调收缩频率及远段胃收缩运动进行统计分析,同时比较观察组患儿治疗前后胃排空50%时间(GET1/2)及2h胃残留率.结果观察组GET1/2为(60.2±12.69)min,观察组90min、120min胃排空率为(61.9±12.2)%、(72.0±12.3)%,均显著优于对照组,差异有统计学意义(t=15.092、14.882,P=0.024、0.033);观察组胃窦幽门协调收缩频率、胃窦收缩频率、胃窦收缩幅度分别为(1.1±0.7)次/min、(2.9±0.8)次/min、(1.0±0.6)cm,均显著优于对照组(t=16.092、21.224、8.092,P<0.05);观察组71例患儿中,治疗前、治疗后GET1/2分别为(68.1±11.8)min、(54.2±9.8)min;治疗前、治疗后2h胃残留分别为(31.2±8.0)%、(22.1±7.0)%,患儿在治疗后GET1/2及2h胃残留率明显低于治疗前,治疗前后差异有统计学意义(t=18.983、21.004,均P<0.05).结论超声VOCAL技术可以作为小儿FD的评估标准.

Objective To evaluate the clinical value of three-dimensional ultrasound VOCAL technique in evaluating gastric emptying function in children with functional dyspepsia ( FD).Methods Seventy-one children with FD who were treated in Wenzhou Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine from January 2018 to June 2018 were enrolled as the study subjects (observation group), and 71 normal children without FD were selected as controls ( control group). The gastric emptying,antral pyloric systolic contraction frequency and distal gastric contraction movement in different time groups were analyzed,and GET1/2 and 2h gastric residual situation before and after treatment in the observation group were compared.Results The GET1/2 of the observation group was (60.2 ± 12.69) min,and the gastric emptying rate of the observation group was (61.9 ± 12.2) min and (72.0 ± 12.3) min at 90min and 120min,which were significantly better than those of the control group, and the differences were statistically significant ( t =19.092, 15.092,14.882, P =0.016,0.024,0.033 ). The frequency of antral pyloric systolic contraction, gastric antrum contraction frequency and gastric antrum contraction amplitude were (1.1 ± 0.7)times/min,(2.9 ± 0.8)times/min, (1.0 ± 0.6) cm, respectively. Compared with the control group,the differences were statistically significant ( t =16.092,21.224,8.092,all P<0.05).In the observation group of 71 children:GET1/2 before treatment and after treatment were (68.1 ± 11.8) min,(54.2 ± 9.8) min,respectively.The gastric residual at 2h after treatment was (31.2 ± 8.0)%, (22.1 ± 7.0)%, respectively. The GET1/2 and 2h gastric residual rate of the children were significantly lower than before treatment,and the differences were statistically significant (t=18.983,21.004,all P<0.05).Conclusion Three-dimensional ultrasound VOCAL technology can be used as an evaluation standard for FD in children.