摘要
患者女,42岁。因"宫颈癌术后近10年,发现外阴肿块1年"入院就诊。查体见双侧大阴唇处各见一疣状赘生物,左侧大小2.5 cm×2.0 cm,右侧大小约5 cm×2 cm,高出皮肤表面约1 cm。表面呈半透明融合水疱样,触之易破,见淡黄清亮液体流出。活检镜下见表面鳞状上皮增生伴角化过度、角化不全,真皮浅层淋巴管呈囊状扩张,内见淡粉染液体及少许淋巴细胞。免疫组织化学示扩张淋巴管D2-40、CD34阳性,CD31、第八因子相关抗原阴性。病理诊断:外阴淋巴管瘤。病史、临床和病理学表现均比较典型,可符合获得性淋巴管扩张症。本例的一个突出特点是病变范围较大。
作者
孙瑶
毛愉燕
吕卫国
吕炳建
Sun Yao;Mao Yuyan;Lyu Weiguo;Lyu Bingjian(Department of Surgical Pathology, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China;Department of Gynecological Oncology, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China;Center for Uterine Cancer Diagnosis & Therapy Research of Zhejiang Province, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China;Women′s Reproductive Health Laboratory of Zhejiang Province, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China)
出处
《中华病理学杂志》
CAS
CSCD
北大核心
2019年第7期566-567,共2页
Chinese Journal of Pathology