Primary lung mucosa-associated lymphoid tissue lymphoma accompanied by multiple sclerosis:case report and molecular diagnosis

To the Editor:Mucosa-associated lymphoid tissue(MALT)lymphoma arises at a wide range of different extranodal sides,including the stomach(70%),lung(14%),ocular adnexa(12%),thyroid(4%),and small intestine.[1,2]Most lung MALT lymphoma are marginal zone B-cell lymphoma with proliferation of small irregular monocytoid B cells around and between reactive lymphoid follicles,with extensive invasion of the lung parenchyma,forming lymphoepithelial lesions.Immunohistochemical analysis showed the positive staining for CD20 and Bcl-2 and negative staining for CD3,CD5,CD23,and CD10 in the neoplastic cells.