免疫球蛋白黄斑病变研究现状

Immunogammopathy maculopathy

免疫球蛋白黄斑病变是近年新发现的一种与巨球蛋白血症相关的视网膜病变。以血液高粘度所致的视网膜静脉纡曲、扩张以及视网膜层间积液、黄斑区浆液性脱离等为主要表现。随病程延长,脱离区光感受器细胞层与 RPE 层出现萎缩改变。眼部发病机制尚不明,了解该病的临床特征、诊断和鉴别诊断、治疗等,对认识该类疾病,提高其诊疗水平有重要意义。

Immunogammopathy maculopathy is a newly discovered retinopathy associated with macroglobulinemia in recent years. The main manifestations were retinal vein convulsion and dilation caused by high blood viscosity, retinal interlaminar effusion and macular serous detachment. With the prolongation of the course of disease, the photoreceptor layer and RPE layer in the detachment area showed atrophic changes. The pathogenesis of ophthalmopathy is still unknown. Understanding the clinical features, diagnosis, differential diagnosis and treatment of ophthalmopathy is of great significance for understanding this kind of disease and improving the level of diagnosis and treatment of ophthalmopathy.