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非感染性肝病与肝癌癌前病变研究进展 被引量:8

Advances in the study of non-infectious liver diseases and precancerous lesions of hepatocellular carcinoma
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摘要 肝细胞肝癌(HCC)是恶性程度很高、预后极差、严重危害人类健康的重大疾病。慢性病毒性肝炎(乙型、丙型肝炎)-肝硬化-肝癌的发病模式已为大家广泛接受。然而,非感染性肝病与HCC的关系尚不完全清晰,各种非感染性肝病如何经过癌前病变进展为HCC引起广泛关注。充分认识这些癌前病变可望为非感染性肝病相关HCC的防治提供新的思路和策略。 Hepatocellular carcinoma (HCC) is a major disease with a high degree of malignancy, and poor prognosis, which seriously endangers human health. Chronic viral hepatitis (HBV, HCV)-cirrhosis-liver cancer patterns of pathogenesis has been widely accepted. However, the relationship between non-infectious liver disease and HCC is not completely clear;thereby how various non-infectious liver diseases develop through precancerous lesions has attracted widespread attention to HCC. A full understanding of these precancerous lesions is likely to provide new ideas and strategies for the prevention and treatment of non-infectious liver disease-related HCC.
作者 颜士岩 范建高 Yan Shiyan;Fan Jiangao(Department of Gastroenterology,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2019年第7期487-490,共4页 Chinese Journal of Hepatology
基金 国家科技部精准诊疗课题(2017YFC0908903) 国家自然科学基金(81470840、81873536、81071888).
关键词 肝病 非感染性 脂肪肝 非酒精性 酒精性肝病 肝细胞 癌前病变 Non-infectious liver diseases Fatty liver, nonalcoholic Alcoholic liver disease Hepatocellular carcinoma Precancerous lesions
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