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拮抗剂方案用于卵巢储备功能低下患者的临床价值

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摘要 目的:探析在卵巢储备功能低下患者中应用拮抗剂方案的临床价值。方法:从佛山市妇幼保健院2016年1月至2017年12月收治的卵巢储备功能低下患者择取856例为研究对象,按照控制性促排方案差异将其分成两组,对照组428例患者行以微刺激方案,观察组428例患者行以拮抗剂方案,比较分析两组临床效果。结果:观察组患者促性腺激素(Gn)总量高于对照组,但组间比较,差异无统计学意义(P> 0.05);观察组患者获得卵数、成熟卵数、可利用胚胎数、优质胚胎数均比对照组高;取消周期率、流产率低于对照组,组间比较,差异具有统计学意义(P <0.05);两组患者鲜胚临床妊娠率比较,差异无统计学意义(P> 0.05);观察组患者累积临床妊娠率、累积活产率均比对照组高,差异具有统计学意义(P <0.05)。结论:对于卵巢储备功能低下患者来说,拮抗剂方案的临床疗效更佳,可以获得良好妊娠结局。
出处 《深圳中西医结合杂志》 2019年第10期144-146,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
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  • 1徐千花,曹云霞,魏兆莲,丛林,章志国.不同促排卵方法在卵巢储备功能下降患者中的应用[J].生殖与避孕,2009,29(1):51-54. 被引量:28
  • 2陈华,孙海翔,胡娅莉,王玢,王俊霞,陈骞.生长激素在体外受精胚胎移植的作用[J].江苏医药,2006,32(5):479-480. 被引量:3
  • 3Fen'aretti AP, La Marca A, Fauser BC,et al. ESHRE Working Group on Poor Ovarian Response Definition. ESHRE consensus on the definition of ' poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria [ J 1. Hum Reprod,2011,26 (7):1616-1624. 2015,35(2) :71-79.
  • 4Davar R, Oskouian H, Ahmadi S,et al. GnRH antagonist/letro- zole versus mic rodose GnRH agonist flare protocol in poor re- sponders undergoing in vitro fertilization :J:. Taiwan J Obstet Gynecol,2010,49 (3) : 297-301.
  • 5Polyzos NP, Devroey P. A systemic review of randomized trials for the treatment of poor ovarian responders: is there any light at the end of the tunnel? [J].Fertil Steril,2011,96(5):1058-1061.
  • 6Khalaf Y, E1-Toukhy T, Taylor A,et al. Increasing the gonadotro- phin dose in the course of an in vitro fertilization cycle does not rectify an initial poor response [J ]. Eur J Obstet Gynecol Reprod Biol,2002,103 (2):146-149.
  • 7Mutlu MF, Erdem M, Erdem A,et al. Antral follicle count deter- mines poor ovarian response better than anti-mullerian hormonebut age is the only preditor for live birth in in vitro fertilization cycles[J ]. J Assist Reprod Genet,2013,30(5):657-665.
  • 8Broer SL, van Disseldorp J, Broeze KA,et al. Added value of ovar- ian reserve testing on patient characteristics in the prediction of ovarian response and ongoing pregnancy: an individual patient data approach[J]. Hum Reprod Update,2013,19(1):26-36.
  • 9Rosen MP, Johnstone E, McCuloch CE,et al. A characterization of the relationship of ovarian reserve markers with age [ J ].Fertil Steril,2012, 97(1 ):238-243.
  • 10Bhattacharya S, Maheshwari A, Mollison J.Factors associated with failed treatment: an analysis of 121744 women embarking on their first IVF cycles[J]. PLoS One,2013,8(12):82249.

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