高分辨率CT肺气肿定量测定对慢性阻塞性肺疾病严重程度的评估价值

Value of high resolution CT emphysema to evaluate the severity of chronic obstructive pulmonary disease

目的探讨高分辨率CT肺气肿定量测定对慢性阻塞性肺疾病(COPD)严重程度的评估价值。方法回顾性收集郑州市中医院2017年1月至2018年6月收治的COPD患者50例作为研究对象,均使用高分辨率CT进行肺气肿的定量检测,整理不同分级COPD患者的各项指标。结果随着COPD患者病情的加重,肺气肿容积占全肺比例(LAA%)也逐渐提高(P<0.05)。而1秒用力呼气容积(FEV1)、FEV1/用力肺活量(FVC)降低(P<0.05)。LAA%与FEV1、FEV1/FVC均呈负相关关系(P均<0.05)。结论高分辨率CT进行肺气肿定量测定有助于临床医师评估慢性阻塞性肺疾病的病情严重程度,预测肺功能变化,有利于及早发现肺功能受损,为临床医师的治疗提供可靠依据,值得推广。

Objective To investigate the value of the emphysema quantitative on high resolution CT to evaluate the severity of chronic obstructive pulmonary disease (COPD). Methods A retrospective study on 50 patients with chronic obstructive pulmonary disease admitted in Zhengzhou Traditional Chinese Medicine Hospital from January 2017 to June 2018 was conducted. High resolution CT was used emphysema, and to collate the indicators of patients with COPD in different grades. Results With the aggravation of COPD, the proportion of emphysema volume to total lung volume (LAA) increased gradually (P<0.05);forced expiratory volume in 1 second (FEV1) and ratio of FEV1 to forced vital capacity (FEV1/FVC) decreased significantly (P<0.05). LAA% and FEV1, FEV1/FVC had negative correlation (P<0.05). Conclusions Quantitative determination of emphysema by high resolution CT is helpful for clinicians to evaluate the severity of COPD, predict the changes of pulmonary function, detect impaired pulmonary function in early, and provide reliable basis for clinical treatment, which is worth popularization.