急诊应用胺碘酮治疗冠心病并发快速心律失常的效果

Effect of emergency treatment of amiodarone on coronary heart disease complicated with tachyarrhythmia

目的探讨急诊应用胺碘酮治疗冠心病并发快速心律失常的价值。方法随机选择临汾市中心医院2016年8月至2018年8月收治的62例冠心病并发快速心律失常患者作为研究对象。将患者随机分为两组,每组31例。试验组给予常规急诊抢救和胺碘酮治疗,对照组给予常规急诊抢救和利多卡因治疗。观察两组心功能指标、总有效率及不良反应发生率。结果治疗后,两组的各项指标均得到了明显的改善,且试验组患者的每搏输出量、心输出量、射血分数等心功能指标改善更明显(P<0.05)。试验组的总有效率(93.55%)高于对照组(80.65%),差异有统计学意义(P<0.05)。实验组不良反应(12.90%)低于对照组(29.03%),差异有统计学意义(P<0.05)。结论急诊应用胺碘酮治疗冠心病并发快速心律失常可有效改善患者的心肌缺血症状,促进患者的心脏功能好转,预防疾病进一步加重,具有积极的临床推广意义。

Objective To investigate the value of emergency treatment of amiodarone on coronary heart disease complicated with tachyarrhythmia. Methods Sixty-two patients with coronary heart disease complicated with tachyarrhythmia in Linfen Central Hospital from August 2016 to August 2018 were randomly selected as the study subjects. The patients were randomly divided into two groups, with 31 cases in each group.The experimental group received routine emergency rescue and amiodarone treatment, and the control group received routine emergency rescue and lidocaine treatment. The cardiac function indexes, total effective rates and incidences of adverse reactions were observed in the two groups. Results After treatment, the indexes of the two groups were significantly improved, and the stroke volume, cardiac output, ejection fraction and other cardiac function indexes were better in the experimental group, and the differences were significant (P<0.05). The total effective rate in the experimental group (93.55%) was higher than that in the control group (80.65%), and the difference was significant (P<0.05). The incidence of adverse reactions in the experimental group (12.90%)was lower than that in the control group (29.03%), the difference was significant ( P<0.05). Conclusions The use of amiodarone in the emergency department for the treatment of coronary heart disease complicated with tachyarrhythmia can effectively improve the myocardial ischemic symptoms, promote the improvement of patients’ heart function, prevent the disease from further aggravating, and it have positive clinical promotion significance.