胶体酒石酸铋联合兰索拉唑治疗幽门螺杆菌阳性胃溃疡的临床疗效

Clinical Efficacy of Colloidal Tartrate Combined with Lansoprazole in the Treatment of Helicobacter Pylori Positive Gastric Ulcer

目的分析胶体酒石酸铋联合兰索拉唑治疗幽门螺杆菌阳性胃溃疡的临床疗效。方法选取我院2016年1月-2018年1月收治幽门螺杆菌阳性胃溃疡患者86例,随机分成对照组与观察组,每组43例。对照组患者接受胶体酒石酸铋治疗,观察组患者在对照组治疗的基础上联合兰索拉唑治疗。比较两组患者临床疗效、临床疗效、状评分。结果观察组患者临床总有效率高于对照组(P<0.05)。观察组患者呕吐、腹胀、反酸、腹痛评分低于对照组(P<0.05)。观察组患者不良反应发生率高于对照组(P>0.05)。结论胶体酒石酸铋联合兰索拉唑是治疗幽门螺杆菌阳性胃溃疡重要途径,能显著降低不良反应发生率、缓解临床症状、提高临床治疗有效率。

Objective To investigate the efficacy of colloidal tartrate combined with lansoprazole in the treatment of Helicobacter pylori positive gastric ulcer.Methods 86 patients with Helicobacter pylori-positive gastric ulcer admitted to our hospital from January to February 2018 were selected and randomly divided into control group and observation group,each with 43 cases.The control group was treated with colloidal tartrate,based on this,the observation group was treated with lansoprazole.Then the clinical efficacy,clinical efficacy and symptom scores of the two groups were compared.Results The total clinical effective rate of the observation group was significantly higher than that of the control group(P<0.05).The scores of vomiting,abdominal distension,acid reflux and abdominal pain in the observation group were significantly lower than those in the control group(P<0.05).The incidence of adverse reactions was higher in the observation group than in the control group(P>0.05).Conclusion The application of colloidal tartaric acid combined with lansoprazole is an effective way to reduce the incidence of adverse reactions and relieve clinical symptoms for patients with Helicobacter pylori positive gastric ulcer.