糖尿病肾病诊疗进展

Progress in diagnosis and treatment of diabetic kidney disease

糖尿病肾病(diabetic kidney disease,DKD)是糖尿病的主要并发症,晚期1/3的患者可进展至尿毒症,严重危害人们健康。近年来随着我国人民生活水平的提高,糖尿病发病率不断增加,目前已成为我国终末期肾脏病的主要原因。近20年来,人们对DKD的诊断与治疗认识也不断提高,例如提出了无蛋白尿DKD新概念以及研发了多种新型抗糖尿病药物等,但目前仍然以健康生活方式、控制血糖、控制血压、调节血脂为DKD治疗的基本策略。

Diabetic kidney disease (DKD) is a major complication of diabetes mellitus. One third of patients with advanced diabetes mellitus can develop to uremia,which seriously endangers people’s health. In recent years,with the improvement of people’s living standards and the increasing incidence of diabetes,it has become the main cause of end stage renal disease in China. Over the past two decades,the understanding of diagnosis and treatment of DKD has been improved,such as putting forward the new concept of normoalbuminuric DKD and developing a variety of new anti-diabetic drugs. However,at present,the basic strategies of DKD treatment are still lifestyle modification,glucose control,blood pressure control and lipid control.