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探究小剂量肾上腺素联合瑞利珠单抗在急救治疗重症哮喘中的临床疗效及预后 被引量:7

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摘要 目的探究小剂量肾上腺素联合瑞利珠单抗在急救治疗重症哮喘中的临床疗效及预后.方法选取某院2017年1月~2018年12月收治的62例重症哮喘患者作为研究对象,按数字随机表法分为对照组31例和观察组31例.两组均采取常规急诊抢救措施,在此基础上对照组单独采用小剂量肾上腺素治疗,观察组采用小剂量肾上腺素联合瑞利珠单抗治疗,比较两组的临床疗效和急救前后的各项预后指标(HR,RR,SaO2和FEV1%).结果对照组临床急救总有效率为74.19%(23/31),观察组临床急救总有效率为93.55%(29/31),观察组高于对照组,差异有统计学意义(P<0.05).急救前,对照组和观察组HR、RR、SaO2、FEV1%比较,差异无统计学意义(P>0.05);急救后,两组HR和RR低于急救前,SaO2和FEV1%高于急救前,差异有统计学意义(P<0.05);观察组HR和RR均低于对照组,SaO2和 FEV1%均高于对照组,差异有统计学意义(P<0.05).结论小剂量肾上腺素联合瑞利珠单抗应用在重症哮喘的临床治疗中疗效显著,可改善患者的预后指标.
出处 《中国处方药》 2019年第8期75-76,共2页 Journal of China Prescription Drug
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