肝转移的肾上腺皮质腺癌1例报道并文献复习

Adrenal cortical adenocarcinoma with hepatic metastasis: A case report and literature review

回顾性分析1例肝转移的肾上腺皮质腺癌(adrenocortical carcinoma,ACC)术前及术后的相关临床资料及相关文献。Weiss评分是ACC最常用的病理学诊断标准。本文1例患者术前增强CT考虑肝癌,术前肝穿刺活检示肝细胞肝癌。术后免疫组织化学结果示CD56和突触小泡蛋白(Syn)阳性,结果考虑ACC。术后行奥沙利铂/卡培他滨(oxaliplatin/capecitabine)化学治疗。随访至2019年2月14日,患者无不适,未见复发及转移。

We analyzed the clinical data of a patient with liver metastasis of adrenocortical carcinoma retrospectively, and reviewed interrelated literatures. We investigated the diagnosis, treatment method and prognosis of the liver metastasis of adrenocortical carcinoma. Weiss score system is the most commonly used criteria for pathological diagnosis. The patient was considered to hepatocellular carcinoma by contrast-enhanced CT. Preoperative liver biopsy revealed hepatocellular carcinoma. Immunohistochemistry results showed the tumor cells were positive for CD56 and Syn;and the result is ACC after operation. The patient has oxaliplatin/capecitabine chemotherapy after liver operation. We didn’t find recurrence or metastasis, and the patient didn’t feel uncomfortable up to 14 February 2019.