利奈唑胺治疗金黄色葡萄球菌感染的疗效分析

Efficacy of Linezolid in the Treatment of Staphylococcus Aureus Infection

目的探讨利奈唑胺治疗金黄色葡萄球菌感染的疗效和安全性。方法选择2018年3月—2019年3月在我院接受诊疗的100例金黄色葡萄球菌感染患者作为研究对象。采取随机分组的方式,将其均分为观察组及对照组,每组各50例。对照组采取万古霉素进行治疗,观察组采取利奈唑胺进行治疗,对比两组临床疗效和不良反应发生情况。结果观察组的总体有效率及不良反应发生率分别为100.00%、6.00%;对照组的总体有效率和不良反应发生率分别为88.00%、18.00%,观察组的总体有效率及不良反应发生率均优于对照组,两组数据比较,差异具有统计学意义(P<0.05)。结论金黄色葡萄球菌感染患者采取利奈唑胺治疗,能够提升治疗效果,并减少不良反应的出现。

Objective To investigate the efficacy and safety of linezolid in the treatment of Staphylococcus aureus infection. Methods 100 patients with Staphylococcus aureus infection who were diagnosed and treated in our hospital from March 2018 to March 2019 were selected as the study subjects. They were randomly divided into observation group and control group with 50 cases in each group. The control group was treated with vancomycin and the observation group was treated with linezolid. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate and the incidence of adverse reactions in the observation group were 100% and 6%, respectively. The overall effective rate and the incidence of adverse reactions in the control group were 88% and 18%, respectively. The overall effective rate and the incidence of adverse reactions in the observation group were better than those in the control group. There were significant differences between the two groups, with statistical significance (P < 0.05). Conclusion Linazolamide treatment for Staphylococcus aureus infection can improve the therapeutic effect and reduce the occurrence of adverse reactions.