卡前列素氨丁三醇注射液联合缩宫素预防高危产妇剖宫产产后出血的临床研究

Clinical study on prevention of postpartum hemorrhage by cesarean section in high risk women with carboprost tromethamine injection combined with oxytocin

目的探究采用卡前列素氨丁三醇注射液联合缩宫素预防高危产妇剖宫产产后出血的应用效果。方法选择本院高危产妇总计112例为对象开展研究,按照随机法将产妇分为研究组与对照组,各56例。两组均采用缩宫素,研究组加入卡前列素氨丁三醇注射液治疗,观察两组患者术后2h、24h的出血量,记录两组不良反应情况。结果研究组各时间段内的出血量相较对照组更低,数据对比差异有统计学意义(P<0.05);对照组不良反应率为7.14%,研究组为10.17%,两组不良反应发生率较小,且两组数据相近,组间比较差异无统计学意义。结论应用卡前列素氨丁三醇注射液联合缩宫素能够显著预防高危产妇剖宫产出血症状,且用药较为安全。

Objective To explore the application effect of Carboprost tromethamine injection combined with oxytocin in preventing postpartum hemorrhage of high-risk parturient by cesarean section.Methods A total of 112 high risk parturients in our hospital were selected.They were randomly divided into study group and control group,with 56 cases in each group.Both groups were treated with oxytocin,the study group was treated with carboprost tromethamine injection.The blood loss was observed at 2 h and 24 h after operation,and the adverse reactions were recorded in both groups.Results The amount of blood loss in the study group was lower than that in the control group(P<0.05),and the odds of adverse reaction in the control group was 7.14%,10.17%adverse reactions in the study group,and the data of the two groups were similar,there was no significant difference between the two groups.Conclusion The application of carboprost tromethamine injection combined with oxytocin can significantly prevent bleeding symptoms of cesarean section in high-risk women,and it is safe to use drugs.