经导管动脉栓塞联合普萘洛尔治疗婴幼儿血管瘤疗效观察

Therapeutic effect of transcatheter arterial embolization combined with propranolol on infantile hemangioma

目的观察采用经导管动脉栓塞(TASE)联合普萘洛尔治疗婴幼儿血管瘤患儿的临床疗效。方法回顾性分析广西壮族自治区人民医院普通介入科2014年1月至2018年1月收治的30例婴幼儿血管瘤患儿的临床资料,15例按常规进行经导管动脉栓塞(TASE)治疗者作为对照组,15例按常规经导管动脉栓塞治疗且同时服用普萘洛尔(用法:3次/d,每次剂量0.5 mg/kg,疗程3~6个月)者作为观察组。治疗后随访3~6个月,随访期结束后比较两组患儿的治疗效果。结果观察组患儿的治疗总有效率为60.00%,高于对照组的26.67%,差异有统计学意义(P<0.05)。结论采用经导管动脉栓塞联合普萘洛尔治疗婴幼儿血管瘤患儿疗效显著,可在临床治疗中推广使用。

Objective To observe the clinical efficacy of transcatheter arterial embolization(TASE) combined with propranolol in the treatment of infantile hemangiomas. Methods A retrospective analysis was performed on clinical data of 30 infants with hemangioma admitted to the Department of General Interventional at the People’s Hospital of Guangxi Zhuang Autonomous Region from January 2014 to January 2018. Fifteen patients who underwent conventional transcatheter arterial embolization(TASE) were used as control group, and 15 patients who underwent conventional TASE and received propranolol(Dosage: 0.5 mg/kg three times daily for 3 to 6 months) were used as observation group.The patients were followed up for 3 to 6 months after treatment, then the therapeutic effects were compared between the two groups. Results The total effective rate of treatment in the observation group was 60.00%, which was higher than26.67% in the control group, and the difference was statistically significant(P<0.05). Conclusion Transcatheter arterial embolization combined with propranolol is effective in the treatment of infantile hemangioma, which can be used in clinical treatment.