腹腔镜手术治疗急性结石性胆囊炎对炎性因子水平与胃肠功能的影响

The Effect of Laparoscopic Cholecystectomy on Inflammatory Factors and Gastrointestinal Function in Patients with Acute Calculous Cholecystitis

目的:探析急性结石性胆囊炎患者采取腹腔镜手术治疗对炎性因子及胃肠功能的影响。方法:本次研究74例急性结石性胆囊炎患者均为笔者所在医院2018年2-11月收治,根据先后入院时间分为两组,对照组(n=37)实施开腹手术,研究组(n=37)进行腹腔镜手术,统计各组胃肠功能指标及炎性因子水平。结果:研究组肛门排便时间、肛门排气时间及肠鸣音恢复时间均低于对照组,差异均有统计学意义(P<0.05);治疗前两组IL-6、TNF-α及hs-CRP水平比较差异无统计学意义(P>0.05),治疗后研究组均优于对照组,差异均有统计学意义(P<0.05)。结论:急性结石性胆囊炎疾病治疗过程中,通过腹腔镜手术有助于胃肠功能改善,减轻炎症病症。

Objective:To investigate the effect of laparoscopic cholecystectomy on inflammatory factors and gastrointestinal function in patients with acute calculous cholecystitis.Method:A total of 74 patients with acute calculous cholecystitis were admitted to our hospital from February to November 2018.According to the admission time,they were divided into two groups on average.The control group(n=37) underwent open surgery,and the research group(n=37) underwent laparoscopic surgery.The gastrointestinal function indexes and inflammatory factors in each group were counted.Result:The anal defecation time,anal exhaust time and intestinal sound recovery time in the study group were significantly lower than those in the control group(P<0.05).There was no significant difference in the levels of IL-6,TNF-α and hs-CRP between the two groups before treatment(P>0.05),but the study group was superior to the control group after treatment,and the difference was statistically significant(P<0.05).Conclusion:Laparoscopic cholecystectomy can improve gastrointestinal function and alleviate inflammation during the treatment of acute calculous cholecystitis.