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两种新辅助化疗治疗乳腺癌的疗效及对预后的影响 被引量:2

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摘要 目的:探讨两种新辅助化疗治疗乳腺癌的临床疗效及预后。方法:选取2014年4月至2016年7月在我院治疗的中晚期乳腺癌患者110例,根据患者选取的治疗方式分为TE组(n=51)和TEC组(n=59),TE组给予多西他赛+表柔比星方案化疗,TEC组给予多西他赛+表柔比星+环磷酰胺方案化疗,观察两组治疗疗效及预后。结果:TE组和TEC组近期疗效差异比较无统计学意义(P>0.05),TE组和TEC组近期总有效率分别为86.27%和89.83%;TE组和TEC组胃肠道反应、肝功能异常、心脏毒性、脱发、血小板减少和手足综合征差异比较无统计学意义(P>0.05);TEC组中性粒细胞减少发生比例为69.49%,明显高于TE组(P<0.05);TEC组中位生存时间为40.32个月,明显高于TE组的36.66个月,差异比较有统计学意义(P<0.05)。结论:乳腺癌新辅助化疗中,TE和TEC方案疗效相似,其中TEC组中位生存时间较长,值得临床推广应用。
作者 王静 赵虎
出处 《黑龙江医药》 CAS 2019年第4期842-844,共3页 Heilongjiang Medicine journal
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