善得定联合洛赛克治疗肝炎后肝硬化并上消化道出血的护理

Nursing care patients with post-hepatitis cirrhosis complicated with upper gastrointestinal bleeding treated by Sandostatin and Losec

目的探讨善得定联合洛赛克治疗肝炎后肝硬化并上消化道出血的护理效果。方法选取2017年10月至2018年10月本院收治的肝炎后肝硬化并上消化道出血患者88例,随机分为两组;两组均进行善得定、洛赛克联合治疗,同时对照组进行常规护理,研究组进行饮食、心理、用药、生活作息、出院指导等针对性护理。比较两组患者抑郁、焦虑评分、总蛋白(TP)、血浆白蛋白(ALB)、体质指数(BMI)等营养指标水平及出血次数、出血率、平均止血时间、止血有效率。结果 研究组患者出院后抑郁评分为(41.7±6.6)分、焦虑评分为(42.3±11.2)分,对照组出院后抑郁评分为(48.4±5.5)分、焦虑评分为(47.6±9.1)分,研究组抑郁、焦虑评分均低于对照组(均P<0.05);研究组患者治疗2周后TP为(59.5±6.7)g/L、ALB为(38.8±5.2)g/L、BMI为(22.9±3.8)kg/m2,对照组患者治疗2周后TP为(52.8±5.9)g/L、ALB为(36.4±4.8)g/L、BMI为(21.8±3.7)kg/m2,研究组TP、ALB、BMI等营养指标水平均高于对照组(均P<0.05);研究组出血次数为(1.1±0.2)次、对照组为(2.5±0.8)次,研究组出血率为6.8%、对照组为22.7%,研究组止血时间为(13.6±5.5)h、对照组为(32.3±7.7)h,研究组止血有效率为95.5%、对照组为86.4%,研究组出血次数、出血率、止血时间均小于对照组(均P<0.05),研究组止血有效率高于对照组(P<0.05)。结论 善得定联合洛赛克治疗肝炎后肝硬化并上消化道出血的护理中,针对性护理效果显著,值得在临床上多加推广与应用。

Objective To explore the nursing effect of Sandostatin combined with Losec in the treatment of post-hepatitis cirrhosis complicated with upper gastrointestinal bleeding. Methods 88 patients with posthepatitis cirrhosis and upper gastrointestinal bleeding treated at our hospital from October, 2017 to October,2018 were randomly divided into a control group and a study group. Both groups were treated with Sandostatin and Losec;the control group received routine nursing, and the study group nursing targeting at diet, psychology, medication, daily life, and discharge guidance. The nutritional indicators such as depression, anxiety score, total protein (TP), plasma albumin (ALB), and body mass index (BMI) as well as bleeding frequency, bleeding rate, average hemostasis time, and hemostasis efficiency were compared between the two groups. Results The postdischarge depression score and anxiety score were (41.7±6.6) and (42.3±11.2) in the study group, and were (48.4±5.5) and (47.6±9.1) in the control group (both P < 0.05). After 2 weeks of treatment, TP was (59.5±6.7) g/L, ALB was (38.8±5.2) g/L, BMI was (22.9±3.8) kg/m2, and after 2 weeks of treatment, the control group was (52.8±6.7) g/m2. Two weeks after the treatment, the TP, ALB, and BMI were (59.5±6.7) g/L,(38.8±5.2) g/L, and (22.9±3.8) kg/m2 in the study group, and were (52.8±5.9) g/L,(36.4±4.8) g/L, and (21.8±3.7) kg/m2 in the control group (all P < 0.05). The number of bleeding, the bleeding rate, the average time of hemostasis, and the effective rate of hemostasis and were (1.1±0.2), 6.8%,(13.6±5.5) h, and 95.5% in the study group, and were (2.5±0.8), 22.7%,(32.3±7.7) h, and 86.4% in the control group (all P < 0.05). Conclusion Targeted nursing for patients with post-hepatitis cirrhosis and upper gastrointestinal bleeding treated by Sandostatin and Losec is remarkably effecttive, so it is worth being clinically generalized.