高尿酸血症与老年脑梗死的相关性分析

Analysis of the correlation between hyperuricemia and senile cerebral infarction

目的:探讨高尿酸血症(HUA)与老年脑梗死的相关性。方法:选取老年脑梗死患者60例,将其作为观察组;选取同期健康体检者60例,将其作为对照组。比较两组一般情况和各实验室检查指标水平的差异性,并依据血尿酸(SUA)是否正常分为HUA组和正常组,比较其短期预后情况。结果:观察组SUA、SBP、DBP、低密度脂蛋白胆固醇(LDL-C)、纤维蛋白原(FIB)水平均高于对照组,差异有统计学意义(P<0.05)。Logistic多因素回归分析结果显示SUA、FIB、LDL-C可能是老年脑梗死的独立危险因素,差异有统计学意义(P<0.05)。HUA组预后不良发生率高于对照组,差异有统计学意义(P<0.05)。结论:高尿酸血症是老年脑梗死的独立危险因素之一,合并高尿酸血症的老年老梗死患者短期预后较差。

Objective To investigate the correlation between hyperuricemia and senile cerebral infarction. Method Sixty patients with senile cerebral infarction were selected as the observation group.Sixty cases of healthy subjects in our hospital were selected as the control group.The differences between the two groups in general and the level of biochemical indexes were compared,and the short-term prognosis was compared according to whether the SUA was normal and divided into HUA group and normal group. Results The levels of SUA,SBP,DBP,LDL-C and FIB in the observation group were significantly higher than those in the control group ( P <0.05).Logistic multivariate regression analysis showed that SUA,FIB and LDL-C could be independent risk factors for senile cerebral infarction ( P <0.05).The incidence of poor prognosis in HUA group was higher than that in control group ( P <0.05). Conclusion Hyperuricemia is one of the independent risk factors of senile cerebral infarction.The short-term prognosis of elderly patients with hyperuricemia is poor.