芪甲通淋化瘀方治疗前列腺增生症30例

Treating 30 Cases of Benign Prostatic Hyperplasia by Qijia Tonglin Huayu Prescription

目的:观察芪甲通淋化瘀方治疗前列腺增生症(BPH)的临床疗效。方法:将60例BPH患者随机分为2组,每组30例。对照组予以非那雄胺口服,5 mg/次,1次/d。观察组以芪甲通淋化瘀方为基础方进行辨证治疗,每日1剂,水煎早晚分服。2组均以连续用药1个月为1个疗程,连续治疗2个疗程,服药期间禁烟酒。观察2组临床疗效及治疗前后国际前列腺症状(I-PSS)评分、最大尿流率(Qmax)及前列腺体积的变化情况。结果:总有效率观察组为83.3%,对照组为70.0%,2组比较差异有统计学意义(P<0.05)。I-PSS评分、Qmax、前列腺体积治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后组间比较差异也有统计学意义(P<0.05)。结论:芪甲通淋化瘀方治疗BPH可以显著改善临床症状,增加最大尿流量,缩小前列腺体积。

Objective: To observe clinical effects of Qijia Tonglin Huayu prescription in the treatment for benign prostatic hyperplasia(BPH). Methods: Sixty BPH patients were randomized into two groups, 30 cases each group. The control group took finasteride orally, 5 mg each time, once each day. The observation group were treated by syndrome differentiation and taking Qijia Tonglin Huayu prescription as the basic prescription, one dose each day,water decocted and taking in the morning and evening. Both groups were treated for one month as one course, for two course consecutively, no smoking and alcohol during the medication period. To observe clinical effects, I-PSS scores before and after treating, Qmax and the changes of prostate volume between both groups. Results: Total effective rate of the observation group was 83.3%, higher than 70.0% of the control group, and the difference had statistical meaning(P<0.05). The difference showed statistical meaning in the comparisons of I-PSS scores, Qmax and prostate volume within two groups before and after treating(P<0.05);the difference had statistical meaning in the comparisons between both groups after treating(P<0.05). Conclusion: Qijia Tonglin Huayu prescription in the treatment for BPH could notably improve clinical symptoms, increase Qmax and reduce prostate volume.