人性化护理在多西他赛联合胸腺肽α1治疗肺癌中的应用及对患者呼吸动力学的影响

Application of Personalized Nursing in the Treatment of Lung Cancer with Docetaxel Combined with Thymosin α1 and its Effect on Respiratory Dynamics

目的探究在多西他赛联合胸腺肽α1治疗肺癌过程中实施人性化护理对患者呼吸动力学及负性情绪的影响。方法选取2016年3月—2018年8月期间在佳木斯大学附属第一医院治疗的84例肺癌患者作为研究对象,按随机数表法分为对照组和观察组,每组各42例,两组均实施多西他赛联合胸腺肽α1治疗,对照组行常规护理,观察组行人性化护理,比较两组干预前后呼吸动力学指标[胸肺顺应性(CT)、气道峰压(Ppeak)]及焦虑自评量表(SAS)、焦虑自评量表(SDS)评分。结果相比对照组,观察组干预后CT提升,Ppeak降低,SAS、SDS评分较低,差异有统计学意义(P<0.05)。结论在多西他赛联合胸腺肽α1治疗肺癌过程中,实施人性化护理可改善患者呼吸动力学,消除负性情绪,提高化疗效果。

Objective To explore the effect of personalized nursing on respiratory dynamics and negative emotion of patients with lung cancer treated with docetaxel combined with thymosin α1.Methods 84 patients with lung cancer treated in the hospital from March,2016 to August,2018 were randomly divided into two groups, with 42 cases in each group.Both groups were treated with docetaxel combined with thymosin α1,and the control group received routine nursing care.The observation group were given personalized nursing,and the respiratory dynamic indexes [chest and lung compliance(CT),peak airway pressure(Ppeak)],self-rating anxiety scale(SAS),score of self-rating scale(SDS)were compared between the two groups before and after intervention.Results Compared with the control group,the CT increased,the Ppeak decreased ,and the SAS and SDS score was lower in the observation group(P<0.05).Conclusion During the treatment of lung cancer with docetaxel combined with thymosin α1,personalized nursing can improve the respiratory dynamics,eliminate negative emotion,and improve the effect of chemotherapy.