北京地区输入性黄热病急性病程及随访研究

Acute phase and follow-up of imported yellow fever in Beijing

目的对2016年北京地坛医院收治的输入性黄热病急性期及半年、一年随访资料进行分析,提高对输入性黄热病疫情的认识及救治水平。方法收集5例患者流行病学史、病原学、临床资料等并进行描述性分析。结果5例输入性黄热病病例,2例重型,3例轻型,其中死亡1例。重型患者表现为发热伴严重肝肾衰竭、凝血功能障碍等;轻型患者肝损伤、胰腺损伤、血小板降低。半年随访时轻型患者恢复正常,重型患者1年随访时基本恢复。结论黄热病以肝肾损伤为主,存在心脏、胰腺等多器官损伤,甚至危及生命,肝功恢复时间较长,轻型半年内恢复,重型需1年以上恢复,且需警惕发生脂肪肝。

Objective To analyze the data of imported yellow fever in acute phase as well as half a year and one -year follow-up in Beijing Ditan Hospital in 2016,so as to improve understanding of epidemic situation and treatment level of imported yellow fever. Methods Epidemiological history,etiology and clinical data of 5 patients were collected and analyzed. Results There are 5 cases of imported yellow fever,2 of which were severe disease,3 were mild type,1 patient died.Severe patients had fever complicated with severe liver and kidney failure,coagulation dysfunction and so on;and mild patients were with liver and pancreatic damage,and thrombocytopenia.Mild patients recovered after half a year follow-up,and severe patients recovered after one -year follow-up. Conclusion Yellow fever is mainly caused by liver and kidney damage,it can damage heart,pancreas and other organs,even endanger life,the recovery time of liver function is long,recovery time of mild disease is half a year,severe disease needs more than one year,and the occurrence of fatty liver should be vigilant.