感染控制干预对医院多重耐药菌管理的效果观察

Observations on the Effects of Infection Control and Intervention on Multi-drug Resistance Organisms in Hospitals

目的观察感染控制干预(以下简称"感控干预")措施对全院多重耐药菌(Multidrug-Resistant Organism,MDRO感染的防控效果。方法运用目标性监测方法对某综合性医院2015-2017年住院患者的MDRO感染情况进行监测,以评价采取多部门协作式感控干预在多重耐药菌感染控制工作中是否有效,2015年为基线调查阶段(干预前),2016年为干预第1阶段,2017年为干预第2阶段,运用卡方检验对比分析每年各项指标的差异,从而分析该院感控干预措施是否有效。结果 2015、2016、2017年核心防控措施执行率各年度间差异有统计学意义(χ^2=52.28,P<0.05);干预后(2016、2017年)MDRO发病率低于干预前(2015年),且差异有统计学意义(χ^2=7.06,P<0.05);干预后(2017年)MDRO医院感染率低于干预前(2015年),且差异有统计学意义(χ^2=7.55,P<0.05);抗菌药物使用率各年度间差异有统计学意义(χ^2=6.47,P<0.05)。结论该院实行的感控干预措施对MDRO医院感染的防控有效。

Objective To examine the effects of infection control and intervention on the management of Multidrug-Resistant Organism(MDROs) in a hospital setting. Methods We used the method of target monitoring;this research retrospectively investigated the infection status of MDRO in a comprehensive hospital during 2015-2017 in order to evaluate the effectiveness of adopting collaborative strategy in MDRO infection control work. 2015 was the the baseline investigation stage(before intervention),2016 was the first phase of the infection control intervention and 2017 was the second phase of the infection control intervention. This research used chi-square test to compare MDRO related indicators among different years to examine whether the infection control interventions were effective. Results The implementation rate of core preventive and control measures in 2015,2016 and 2017 has significant difference among different yars(χ^2=52.28,P<0.05);The incidence of MDRO after intervention(2016,2017)was lower than that before intervention(2015),and the difference was statistically significant(χ^2=7.06, P<0.05);The nosocomial infection rate of MDRO after intervention(2017) was lower than that before intervention(2015), and the difference was statisticallysignficant(χ^2=7.55,P<0.05);There was significant difference in the usage rate of antibiotics among different years(χ^2=6.47, P<0.05). Conclusion The adopted infection control interventions are effective for preventing and controlling MDRO in hospital settings.