胎儿脑部MR成像T1加权序列的临床应用进展

Clinical application of T1W fetal brain MR imaging

T1加权成像作为胎儿脑部MR检查的常规序列,主要用于评估胎儿脑部发育及显示出血性病变、钙化、蛋白质及脂肪,近年来随着快速扫描序列、采集方法及后处理技术等的发展,胎儿T1加权成像得到了较大程度的提升,主要体现在缩短了成像时间,减少了运动伪影干扰,图像SNR、分辨率及信号对比有了提高,三维T1加权成像及T1定量序列的发展使T1WI在胎儿脑部MR有着较多潜在应用前景。本综述就胎儿脑部T1WI的主要诊断价值、胎儿中枢神经系统的发育特点对T1WI的要求、胎儿脑部T1加权序列发展史及临床应用进展做一综述。

T1WI is a routine sequence for fetal brain MR examination. It is mainly used to evaluate the development of fetal brain, and display hemorrhagic lesions, calcification, protein and fat. In recent years, with the development of fast-se - quence MRI, acquisition method and post-processing technique, fetal T1WI has been greatly improved in the following aspects, shortening acquisition time, reducing motion artifacts and interference, and increasing image resolution and signal to noise ratio (SNR). It is valuable and applicable of 3D, T1-weighted gradient-echo imaging (T1WI) fetal brain MR. This article reviews the diagnostic value of T1WI in fetal brain imaging, the characteristics of fetal central nervous system, the development of T1WI, and the clinical application of T1WI in fetal brain imaging.